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PRESERVE featured on the Kinked Wire podcast

Matthew S. Johnson, MD, FSIR, discussed the current status of inferior vena cava (IVC) filters on a recent Kinked Wire podcast. During this discussion, Dr. Johnson presented an update on the PRESERVE Trial. He provided an enrollment update, timeline of data access and manuscripts as well as the potential impact of the results on the scientific community.
PRESERVE publication highlights its unique design and collaborative support

In October 2019, the PRESERVE Steering Committee published a methodology paper in the Journal of Vascular Surgery: Venous and Lymphatic Disorders. The article focuses on the unique structure of the study and the combined support of various stakeholders, including the Society of Interventional Radiology, the Society for Vascular Surgery, U.S. Food and Drug Administration and several IVC filter manufacturers. Subject enrollment is closed and the study is in the process of completing follow-up visits and data cleaning.
Gillespie DL, Spies JB, Siami FS, Rectenwald JE, White RA, Johnson MS. Predicting the Safety and Effectiveness of Inferior Vena Cava Filters Study: Design of a unique safety and effectiveness study of inferior vena cava filters in clinical practice. J Vasc Surg Venous Lymphat Disord. 2019;pii: S2213-333X(19)30436-6
Bikdeli B, Chatterjee S, Desai NR, Kirtane AJ, Desai MM, Bracken MB, Spencer FA, Monreal M, Goldhaber SZ, Krumholz HM. Inferior Vena Cava Filters to Prevent Pulmonary Embolism: Systematic Review and Meta-Analysis. J Am Coll Cardiol. 2017;70(13):1587-1597
Deso, SE, IA Idakoji, and WT Kuo. Evidence-based evaluation of inferior vena cava filter complications based on filter type (PDF) Semin Invernt Radiol. 2016;33:93-100
DeYoung E, Minocha J. Inferior Vena Cava Filters: Guidelines, Best Practice, and Expanding Indications (PDF) Semin Intervent Radiol. 2017;33(2):65-70
IVC Filters and the Recent Trials – February, 26, 2016
Patient enrollment begins for PRESERVE, a large study of retrievable IVC filters – December 16, 2015
Large-scale study on vein filter use launches – November 12, 2014
FDA Safety Communication: Removing Retrievable Inferior Vena Cava Filters – May 6, 2014
FDA Initial Communication: Removing Retrievable Inferior Vena Cava Filters – August 9, 2010
PRESERVE Study to be a comprehensive evaluation of Inferior Vena Cava Filter Use. Endovascular Today – October 11, 2012
Morales JP, Li X, Irony TZ, Ibrahim NG, Moynahan M, Cavanaugh KJ Jr. Decision analysis of retrievable inferior vena cava filters in patients without pulmonary embolism. J Vasc Surg: Venous and Lym Dis. 2013;1:376-84

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