Completed research studies
Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-directed Thrombolysis (ATTRACT) was the first national multicenter, randomized trial to compare the ability of two treatment strategies, standard treatment (consisting of anticoagulants and the use of elastic compression stockings), and pharmacomechanical catheter-directed thrombolysis (PCDT) in addition to the standard treatment. It was led by Suresh Vedantham, MD, FSIR, of the Mallinckrodt Institute of Radiology, Washington University in St. Louis. ATTRACT successfully enrolled its full target of 692 patients and closed enrollment on Dec. 16, 2014. The 2-year patient follow-up period was completed for the last patient in early 2017. The study’s results were presented at the SIR Annual Scientific Meeting in Washington, D.C., on March 6, 2017, and were subsequently published in the New England Journal of Medicine on Dec. 7, 2017. As of mid-2018, the ATTRACT Steering Committee is continuing to analyze the data and write secondary manuscripts.