The value of clinical research

SIR Foundation Clinical Research and Registries Division strongly encourages the IR community to undertake research initiatives that support evidence-based research and advance patient care. Many opportunities are provided for investigator collaboration, scientific training, and innovation. This division supports the development of research trials, clinical registries, and other research programs to address important clinical questions in IR. Current project stakeholders include academia, hospital centers, federal agencies, industry, medical associations and patient advocacy organizations.



Clinical research

The Clinical Research and Registries Division supports diverse research initiatives in IR. Clinical research involves the investigation of a drug, device or procedure on a specific population to evaluate the effects on health outcomes. The results can be applied to improve patient care and advance medical knowledge. Investigators are encouraged to participate in research studies on critical topics in IR.



Clinical trials

Clinical trials involve the investigation of a drug, device, or procedure on a specific population to evaluate the effects on health outcomes. SIR Foundation supports a variety of studies to advance the specialty of IR. Previous involvement included assisting with subject enrollment and raising general awareness in the IR Community. For more information on SIR Foundation's previous and current trials, please visit the clinical trials page.



Clinical registries

Clinical registries collect standardized data on a specific population defined by a particular disease, condition or procedure. They are valuable in comparing patient data across institutions to improve quality and patient safety. SIR Foundation encourages registry endeavors to collect data for supporting evidence-based research. If you are interested in learning about registries supported by the SIR Foundation, please visit the clinical registries page.



Latest SIR Foundation clinical research news

See the future of research in biliary interventions 

Harjit Singh, MD, FSIR, from Johns Hopkins University alongside Ahsun Riaz, MD, from Northwestern University led the SIR Foundation Research Consensus Panel (RCP) on “Research Priorities in Cholangioscopic and Cholangiographic Interventions.” This meeting took place on March 3rd and 4th via Zoom. Subject matter experts from interventional radiology, diagnostic radiology, gastroenterology, and surgery (adult and pediatric) participated on a panel to discuss and prioritize critical topics in biliary and gallbladder research. The panelists prioritized the following topics for further investigation

  • Percutaneous multimodality management (LASER vs. endobiliary ablation vs. cholangioplasty vs. drain upsize protocol alone) of benign anastomotic biliary strictures;
  • Ablation with and without stenting for intraductal cholangiocarcinoma; and
  • To study cholangioscopy/lithotripsy for non-surgical patients with calculous cholecystitis including recurrence rate of cholecystitis as a primary outcome with safety, tube removal rates, and cost as secondary outcomes.

After the RCP, Dr. Riaz and Dr. Singh will be working on an RCP proceedings paper with the panelists to submit to the Journal of Vascular and Interventional Radiology. For more information, please visit the SIR Foundation RCP and Research Summit website.


The Sacroplasty Registry is searching for new host sites

SIR Foundation is partnering with Talosix in a registry to evaluate the effectiveness of sarcoplasty procedures to collect standardized data to improve patient care. This registry covers the costs for sites to train and submit high-quality data to the sarcoplasty registry. If your site completes 1–2 sacroplasty procedures per month, please visit the registries page to find out how you can participate.


Call for C-TRACT participants

The NIH-sponsored C-TRACT study (Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy) is seeking patients with disabling iliac-obstructive post-thrombotic syndrome. The goal is to determine if the use of image-guided, endovascular therapy will effectively reduce post-thrombotic syndrome disease severity in patients. C-TRACT is looking to enroll more patients, check to see if your patient is eligible to enroll today.