Welcome to the SIR Foundation!













Interventional Oncology Symposium: SIR Foundation and RSNA
November 28 - December 2, 2005

Clinical Science of Interventional Oncology (Monday and Tuesday)

Monday

Liver: Ablation

8:30-8:35

Introduction/Moderation (Gerald D. Dodd III, MD)

8:35-8:45

How I Do It : RFA/MWA (Luigi Solbiatti, MD)

8:45-9:15

Scientific Abstracts: HCC Ablation

Comparing the Outcomes of Surgical Resection and Radiofrequency Ablation in Cirrhotic Patients with a Single Small Hepatocellular Carcinoma and Well-Preserved Hepatic Function - Riccardo A. Lencioni, MD

CT-guided High-dose Percutaneous Ethanol Injection Therapy for Hepatocellular Carcinoma Technically Difficult or Impossible to Treat with US-guided Radiofrequency Ablation - Jung Hyeok Kwon, MD,PHD

Complete Response to Laser Ablation Predicts Long-Term Survival in Patients with Hepatocellular Carcinoma - Claudio M. Pacella MD, MD

9:15-9:25

How I Do It : CRYOABLATION (Peter Littrup, MD)

9:25-9:55

Scientific Abstracts: Non HCC Ablation

Radiofrequency Ablation in Patients with Small (less than 4 cm) Solitary Colorectal Liver Metastases - Alison R. Gillams, MBCHB

Indications and Long term results of laser ablation of Liver metastases of breast cancer - Martin G. Mack, MD

Combination of MR-guided radiofrequency (RF) ablation and neoadjuvant-adjuvant chemotherapy for colorectal liver metastases: A prospective phase II study - Philippe L. Pereira, MD

9:55-10:05

Panel Discussion (Dodd, Solbiati, Littrup)

10:05-10:25

Break

 

Liver: TACE

10:25-10:30

Introduction/Moderation (Michael Soulen, MD)

10:30-10:40

How I Do It : TACE Pt Selection, and Procedure (William Rilling, MD)

10:40-11:10

Scientific Abstracts: TACE HCC

Segmental Lipiodol-TAE: Its role and outcome in the treatment of HCC - Hiroshi Sakaguchi, MD

Hepatocellular carcinoma with biliary tumor thrombi; Survival rates according to the different treatment modalities - Hwan Jun Jae, MD

TransArterial Chemoembolization before Liver Transplantation: Long-Term Clinical Results in a single center experience - Irene Bargellini, MD

11:10-11:20

How I Do It : TACE Complications and Follow-up (Riad Salem, MD)

11:20-11:50

Scientific Abstracts: TACE NonHCC

Intrahepatic Cholangiocellular Carcinoma (ICC) - Comparison of transarterial chemoembolization (TACE) to transarterial chemoperfusion (TACP) - Matthias Heller, MD

Selective Internal Radiation Therapy with Yttrium90 resin microspheres (SIRT-Y) in extended metastatic disease of the liver: initial experiences. - Tobias F. Jakobs, MD

TransArterial ChemoEmbolization (TACE) of neuroendocrine hepatic metastases using drug eluting beads. - Thierry De Baère, MD

11:50-12:00

Panel Discussion (Soulen, Rilling, Salem)

12:00-1:30

Lunch

 

Liver: Guidance and Imaging

1:30-1:35

Introduction/Moderation (Bill Lees, MD)

1:35-1:45

State of the Art : Guidance Techniques (Stephen Solomon, MD)

1:45-2:15

Scientific Abstracts: Guidance & Follow-up

Computed Tomography Images with an Angiographic C-Arm System: Initial Results on Liver Tumor Assessment during Chemoembolization - Frank Wacker, MD

A Novel Workflow Oriented Computer-Assisted Needle Positioning System for Percutaneous Interventions - Markus Nagel, MD

Multiplanar MR-fluoroscopy guided radiofrequency ablation: feasibility and comparison with step-by-step MR imaging. - Philippe L. Pereira, MD

2:15-2:25

How I Do It : Monitoring Techniques (William Lees, MBBS)

2:25-2:55

Scientific Abstracts: Follow-up Sono & CT

Usefulness of SonoVue-enhanced Pulse-Inversion Ultrasonography to assess Hepatocellular Carcinoma response after Percutaneous Radiofrequency Thermal Ablation Therapy - Tommaso V. Bartolotta, MD,PHD

Contrast Enhanced Ultrasound and Contrast Enhanced MRI comparison during efficacy evaluation of Radiofrequency Thermal Ablation of hepatocellular carcinoma - Fabrizio Calliada, MD

Completeness of Treatment in Hepatocellular Carcinomas Treated with Image-Guided Tumor Ablation: Evaluation of Positive Predictive Value of Contrast-enhanced CT with Histopathologic Correlation in the Explanted Liver Specimen - Young-Sun Kim, MD

2:55-3:05

How I Do It : Follow-up MRI (Carlo Bartolozzi, MD)

3:05-3:25

Scientific Abstracts: Follow-up PET/CT

Follow-up of malignant liver tumors treated with radiofrequency ablation: Comparison of PET/CT and MRI - Hilmar Kuehl, MD

The role of PET-CT in interventional therapy of liver tumours - Peter Herzog, MD

3:25-3:35

Panel Discussion (Lees, Solomon, Bartolozzi)

3:35-3:55

Break

 

Liver: Post RX Findings, Complications

3:55-4:00

Introduction/Moderation (David Lu, MD)

4:00-4:10

How I Do It : Post RX Care & Management (David Lu, MD)

4:10-4:40

Scientific Abstracts: Post RX Findings

Study of Recurrence Patterns of Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization - Dai Xu, PHD

Biochemical and Hematologic Alterations Following Percutaneous Cryoablation of Liver Tumors: Experience in 48 Procedures - Rashmi T. Nair, MD

Human growth factor (HGF) evaluation before liver intervention: Long term results of a prognostic significance for liver regeneration. - Thomas Lehnert, MD

4:40-4:50

State of the Art : Combined Therapies (Kamran Ahrar, MD)

4:50-5:10

Scientific Abstracts: Complications

Complications after percutaneous radiofrequency ablation (RFA) of focal hepatic tumors - Ralf-Thorsten Hoffmann, MD

Complications of laser thermal ablation (LTA) for hepatocellular carcinoma: a multicentric study on 520 italian patients - Stefano Pretolani, MD

5:10-5:20

State of the Art : Probes & Generators (Fred Lee, MD)

5:20-5:50

Scientific Abstracts: Probes

Radiofrequency Ablation with Multiple Electrodes: Initial Clinical Experience - Lisa A. Sampson, MD

Bipolar Radiofrequency Ablation Using Internally Cooled Electrodes: An Experimental Study in Ex-vivo Bovine Liver - Stephan Clasen, MD

Simultaneous cool-tip multiprobe RF ablation of multiple liver malignancies under real-time biplane sonographic guidance. - Luigi Solbiati, MD

5:50-6:00

Panel Discussion (Lu, Ahar, Lee)

Tuesday

Kidney: Part 1

8:30-8:35

Introduction/Moderation (Gary Dorfman, MD)

8:35-8:45

State-of-the-Art: Ablative Techniques Overview (Peter Mueller, MD)

8:45-9:15

Scientific Abstracts: Ablative Techniques

Image-Guided Percutaneous Cryoablation of Solid Renal Tumors: An Alternative to Percutaneous RFA - Michael Farrell, MD

Renal cell carcinoma interest of wet bipolar Radiofrequency ablation Afshin Gangi, MD, PhD
Multiple-electrode radiofrequency ablation in the kidney - Lisa A. Sampson, MD

9:15-9:25

How I Do It : Patient and Lesion Selection (J. William Charboneau, MD)

9:25-9:55

Scientific Abstracts: Patient Selection/Follow-up

A cost comparison of laparoscopic versus CT-guided, percutaneous renal tumor cryoablation - Ajay Gupta, MD

Radiofrequency Ablation (RFA) of Large ( 4 cm) Tumors: Experience with 30 Tumors - Debra A. Gervais, MD

MRI follow-up of renal tumors treated with MRI-guided percutaneous cryoablation - Kemal Tuncali, MD

9:55-10:05

Panel Discussion (Dorfman, Charboneau, Mueller)

10:05-10:25

Break

 

Kidney: Part 2

10:25-10:30

Introduction/Moderation (Ronald J. Zagoria, MD)

10:30-10:40

How I Do It: Imaging Follow-up (Debra A. Gervais, MD)

10:40-11:10

Scientific Abstracts: Guidance and Follow-up

Percutaneous MRI-Guided Cryoablation Of Renal Tumors - Stuart G. Silverman, MD

CT-guided percutaneous renal cryoablation under conscious sedation: initial clinical experience - Ajay Gupta, MD

Natural history of early enhancement on MRI after renal tumor cryoablation - Erick M. Remer, MD

11:10-11:20

How I Do It: Clinical Management of Complications (William W. Mayo-Smith, MD)

11:20-11:50

Scientific Abstracts: Follow-up

Contrast-enhanced CT during Radiofrequency Ablation Decreases the Incidence of Incompletely Treated Renal Tumors - Kyle Krehbiel, MD

Radiofrequency Ablation (RFA) of 25 Renal Masses in Patients with Solitary or Functionally Solitary Kidneys: Trends in Creatinine Levels With and Without Obstructive Complications - Debra A. Gervais, MD

Diagnostic Effectiveness of Biopsy prior to Percutaneous Ablation of Renal Tumors - Tatiana C. Coelho da Rocha, MD

11:50-12:00

Panel Discussion (Zagoria, Gervais, Mayo-Smith)

12:00-1:30

Lunch

 

Lung

1:30-1:35

Introduction/Moderation (Damien Dupuy, MD)

1:35-1:45

How I Do It : RF Ablation (Damien Dupuy, MD)

1:45-2:15

Scientific Abstracts: RFA

Radiofrequency Ablation of Pulmonary Tumors Response Evaluation (RAPTURE) Trial: Final Report - Riccardo A. Lencioni, MD

Percutaneous Radiofrequency Ablation of Stage IA Non-Small Cell Lung Cancer: A Prospective Multicenter Clinical Trial - Riccardo A. Lencioni, MD

Radiofrequency Ablation for the Treatment of Unresectable Lung Metastasis in PAtients with Colorectal Cancer: Multicenter study in Japan - Koichiro Yamakado, MD

2:15-2:25

How I Do It : Patient Selection/Avoiding Complications (Eric vanSonnenberg, MD)

2:25-2:45

Scientific Abstracts: Other ablative therapies

Bipolar radiofrequency ablation of lung metastases - Martin G. Mack, MD

Laser-induced thermal ablation of lung metastases: CT findings in a follow-up study - Christian Rosenberg, MD

2:45-2:55

How I Do It : Follow-up (path/imaging/recurrence) (Rob Suh,MD)

2:55-3:15

Scientific Abstracts : Follow-up

Pathomorphological proof of complete Radiofrequency Ablation of pulmonary metastases: Is there a correlation with the ground-glass opacities? - Stephan Clasen, MD

Does the standardized uptake value (SUV) of a lung neoplasm predict its response to radiofrequency ablation? - Don C. Yoo, MD

3:15-3:30

Panel Discussion (Dupuy, vanSonnenberg, Suh)

3:30-3:55

Break

 

Bone

3:55-4:00

Introduction/Moderation (Matthew Callstrom, MD)

4:00-4:10

How I Do It : Patient Selection, Ablation vs. XRT (Matthew Callstrom, MD)

4:10-4:30

Scientific Abstracts : RFA &Cement

Radiofrequency Ablation: An Algorithm for the Treatment of Spinal Mets and Myeloma - Jorge A. Vidal, MD

Radiofrequency Ablation for the Treatment of Osteoblastic Bone Malignancies - Atsuhiro Nakatsuka, MD

4:30-4:40

How I Do It : RFA with Stabilization (Dan Brown, MD)

4:40-5:00

Scientific Abstracts : RFA & Stabilization

Combination of Radiofrequency ablation and percutaneous cementoplasty in painful bone metastasis: Experience in 75 cases - Afshin Gangi, MD, PhD

Combined bipolar radiofrequency and cementoplasty in bone metastasis: preliminary results in 16 Cases - Bruno A. Kastler, MD

5:00-5:10

How I Do It: Cryoablation (Leon D. Rybak, MD)

5:10-5:30

Scientific Abstracts : Cryo

Percutaneous Cryotherapy Treatment of Painful Metastatic Disease Involving Bone: Clinical Trial Interim Analysis. - Matthew R. Callstrom, MD,PHD

MRI-guided Percutaneous Cryotherapy of Bone and Soft Tissue Metastases Adjacent to Critical Structures: Initial Experience in 22 Patients - Kemal Tuncali, MD

5:30-5:45

Panel Discussion (Callstrom, Brown, Ryback)

Innovation and Research in Interventional Oncology (IR)2: Basic Science of Interventional Oncology
(Wednesday, Thursday and Friday)

   
Wednesday

 

8:30-9:40

Tumor Biology for the Radiologist, Part I
Introduction and Hypoxia (Sydney Evans, DVM)
Cell Survival: Proliferation and Apoptosis (Robert G. Bristow, MD, PhD )
Stroma and Interstitial Fluid Pressure (Mary J. Hendrix)

9:40-10:00

Abstracts

Feasibility of BOLD MRI to Monitor Transcatheter Hepatic Artery Embolization of Liver Tumors in the VX2 Rabbit Model - Andrew C. Larson, PHD

Integrin Targeted Nanoparticles for Imaging and Therapeutics with Application in Brain Tumor Models - Samira Guccione, PHD

10:00-10:30

Break

10:30-11:40

Tumor Biology for the Radiologist, Part II
Angiogenesis (William Lee, MD)
Glucose, Lactate, and Tumor pH (Robert Gatenby, MD)
Invasion and Metastasis (Richard Hill)

11:40-12:00

Abstracts

4D Imaging of Hepatic Stellate Cells during Formation of Colorectal Cancer Metastases: A Novel Application for Molecular Imaging - Jonathan B. Kruskal

Combination of radiofrequency with antiangiogenic therapy increases tumor ablation efficacy - S. Nahum Goldberg, MD

12:00-1:00

Lunch Break

1:00-2:00

Animal Models for Image-guided Cancer Therapy
Spontaneous Tumors in Pets (Donald Thrall)
Rodent Model of NF1-induced Brain Tumors (David Gutmann)

2:00-2:30

Abstracts

In vivo Monitoring of Therapeutic Response in a Murine Model of Glioma using Small Animal MR and PET Imaging - Sarah C. Jost, MD

N-nitrosodiethylamine induced pig hepatocellular carcinoma model: Radiological and histopathological studies - Li Xiao

Gene Expression Profiles in tumors treated with focused ultrasound - Walter Hundt, MD

2:30-3:00

Break

3:00-3:30

Tumor Imaging, Part I
Functional MR Imaging and MR Spectroscopy (Gregory S. Karczmar, PhD)

3:30-4:00

Abstracts

A Method for Extracting Sets of Genes Related to Magnetic Resonance Imaging (MRI) Features Significantly Enriched for Known Biological Function - Michael D. Kuo, MD

Radiofrequency (RF) liver ablation with accurate MR temperature mapping - Marko K. Ivancevic, PHD

Ultrafast 1D approach for phase or frequency mapping for MRI-based temperature measurement - Nathan J. McDannold, PHD

4:00-4:30

Break

4:30-4:50

Tumor Imaging, Part II
Molecular Imaging (Umar Mahmood, MD)

4:50-5:20

Abstracts

Imaging of Pancreatic carcinoma orthotopic xenografts in athymic nude mice with a tumor targeting liposomal nanocomplex encapsulating gadopentetate dimeglumine contrast agent - Matthew T. Freedman, MD

In vivo imaging of vaB3: expression in human tumor xenografts using a target specific optical tracer - Christoph B. Bremer, MD

Synthesis and Evaluation of Anti-EGFR Bimodal Contrast Agent for Evaluation of Head and Neck Squamous Cell Carcinoma - Edwin Y. Wang, MD

5:20-5:30

PET in Interventional Oncology (Dominique Delbeke, MD, PhD)

5:30-6:00

Abstracts

Radiofrequency ablation of the rabbit lung VX2 tumor model: FDG-microPET image and histological correlation - Tomohisa Okuma, MD

PET/CT in assessment of liver tissue following radiofrequency ablation: Is there a benefit over morphologic imaging procedures? - Gerald Antoch, MD

PET/CT in Image-Guided Interventions of Liver Malignancies - Gerald Antoch, MD

Thursday

 

8:30-8:55

Tumor Imaging, Part III
Ultra Sound in Interventional Oncology (Martin John Blomley, MD)

8:55-9:15

Abstracts: IO US

Development of a methodology for studying the relationship between tumor tissue perfusion and hypoxia - Nicolas Elie, PHD

Comparing Contrast-Enhanced US Measures of Angiogensis in a Murine Glioma Model - Flemming Forsberg, PhD

9:15-9:40

Real-time US/CT fusion imaging (Riccardo A. Lencioni, MD)

9:40-10:00

Abstracts: IO CT

Monitoring Angiogenic Response in Hepatocellular Carcinoma with Perfusion CT Nagaraj - Setty Holalkere, MD

A contrast investigation between functional CT imaging and molecular pathology on tumor angiogenesis - Jingfeng Zhang, PHD

10:00-10:30

Break

10:30-11:20

Image Guidance for Oncologic Intervention, Part I
Overview of Image Guided for Oncologic Intervention (Ferenc Jolesz, MD)
Image Registration in Neurosurgery (Ron Kikinis, MD)

11:20-12:00

Abstracts

3D Computerized Monitoring of MRI-guided Percutaneous Cryoablations: Validation of the System in an Animal Model and Retrospective Clinical Case Applications - Kemal Tuncali, MD

Image guided surgery - Phantom studies and first results with a novel CT based navigation system (CAPPA® IRad, CAS Innovations AG, Erlangen, Germany). - Ulrich H. Krause, MD

Needle Navigation in a true soft tissue environment using the Medarpa® System; CT Reality Superimposed on the Site of Intervention - Fawad Khan

The real-time MRI (open scanner) guidance and monitoring in Percutaneous laser ablation of liver tumors - Li C. Li

12:00-1:00

Lunch

1:00-2:00

Image Guidance for Oncologic Intervention, Part II
Image Registration in Prostate Cancer Therapy (Clare Tempany, MD)
Image Registration in the Musculoskeletal System (Randy Ellis)
MR-guided Focused Ultrasound Interventions (Kullervo Hynynen, PhD)

2:00-2:30

Abstracts

CT Integrated High-Intensity Focused Ultrasound (HIFU) Navigation System for Drug Delivery or Thermal Ablation Guided by Coregistered CT and Ultrasound - Jeffrey H. Yanof, PHD

Navigated CT guided percutaneous musculoskeletal interventions - Reto J. Bale, MD

SONOPILOT®-THERMO - An ultrasound based integrated system for navigation and therapy control of thermal ablation therapies - Robert Lemor, PHD

2:30-3:00

Break

3:00-3:40

Image Guidance for Oncologic Intervention, Part III
Robotics for Tumor Diagnosis and Therapy (Gabor Fichtinger)
Real-time Guidance for Image-Guided Cancer Therapy (Nobuhilo Hata)

3:40-4:00

Abstracts

Robotic RFA Needle Guidance with Joystick and Laser Controlled Methods in CT - Anand Viswanathan, MS

Evaluation of a MR-compatible robotic instrument guiding system in a porcine model - Andreas Melzer, MD

4:00-4:30

Break

4:30-5:30

Material Science and Drug Delivery

New polymer delivery systems (Justin Hanes, PhD)
Targeted nanoparticles (Justin Hanes, PhD)
Enhancing intracellular penetration of therapeutics (Justin Hanes, PhD)
Drug-eluting beads (Jean-Francois Geschwind, MD)

5:30-6:00

Abstracts

Molecular Imaging-guided Gene and Radiovirotherapy for Pancreatic Cancer - Stephanie K. Carlson, MD

Pulsed-High Intensity Focused Ultrasound (HIFU) enhanced delivery of Doxorubicin using Heat Sensitive Liposome (Thermodox™) - Sergio Dromi, MD

Prolonged Release of Pt in Plasma can be achieved in Transcatheter Arterial Chemoembolization with Powdery Cisplatin Suspension in Lipiodol for Hepatocellular Carcinoma - Yashitaka Tamura, MD,PHD

Friday

 

8:30-9:30

Tumor Ablation Science
Hyperthermia and Thermal Ablation (Mark DeWhirst)
New Devices for Thermal Ablation (Fred T. Lee, MD)
Adjuvant Strategies for Thermal Ablation (S. Nahum Goldberg, MD)

9:30-10:00

Abstracts

Radiofrequency (RF) ablation with adjuvant therapy: Comparison of external beam radiation (XRT) and liposomal doxorubicin (Doxil) on ablation efficacy in an animal tumor model -S. Nahum Goldberg, MD

Measurement of the Thermal Sink Effect in Porcine Kidney, Liver, and Lung During Cryoablation - Stephen Solomon

Triaxial microwave ablation: A small-gauge multiple-antenna system produces large zones of ablation in porcine liver - Lisa A. Sampson

10:00-10:30

Break

10:30-11:20

Catheter-directed Therapies
Intraarterial Delivery of doxorubicIn-eluting microspheres for liver cancer (Jean-Francois Geschwind, MD)
New Drugs for liver cancer delivered intraarterially (Gordon McLennan, MD)
Immunoembolization (Kevin Sullivan, MD)

11:20-12:00

Abstracts

Effects of intraarterial delivery of 3-Bromopyruvate on tumor apoptosis: Comparision of 1hr infusion to serial bolus injections in an animal model of liver cancer. - Jean-Francois H. Geschwind, MD

Renal Embolization: Feasibility of MR-Guidance Using Active Catheter Tracking and Intra-Arterial MR Angiography Peter J. Hallscheidt, MD, PhD
Second-Line Intrarterial Chemotherapy for Advanced Pancreatic Cancer - Orlando Catalano, MD

Experimental study of treatment on VX2 rabbit liver tumor by selectively hepatic artery embolization hyperthermia with Nano Superparamagnetic Iodized Oil - Yang Zhengqiang, MD

 


 

SIR Foundation
3975 Fair Ridge Drive, Suite 400 North, Fairfax, VA 22033
Phone - 703.691.1805 Fax - 703.691.1855
info@SIRFoundation.org

©2008 SIR Foundation. All rights reserved.